The bactericidal function of macrophages against pneumococci is enhanced by their apoptotic demise. which is controlled by the anti-apoptotic protein Mcl-1. Here. we show that lysosomal membrane permeabilization (LMP) and cytosolic translocation of activated cathepsin D occur prior to activation of a mitochondrial pathway of macrophage apoptosis. https://foldlyers.shop/product-category/accessories-probes/