Abstract Argonaute proteins are the central effectors of RNA-guided RNA silencing pathways in eukaryotes. playing crucial roles in gene repression and defense against viruses and transposons. Eukaryotic Argonautes are subdivided into two clades: AGOs generally facilitate miRNA- or siRNA-mediated silencing. while PIWIs generally facilitate piRNA-mediated silencing. https://parisnaturalfoodes.shop/product-category/regenerlife/